Progressive Familial Intrahepatic Cholestasis (PFIC) is a rare liver disorder that starts affecting in early childhood. It is accumulation of bile in the liver cells. Bile formation is vital for liver function, aiding in fat absorption and toxin removal. However, when bile secretion is impaired, it can lead to serious health issues, including liver failure. This can lead to liver damage and a range of health issues. PFIC is typically caused by mutations in genes those regulate the movement of bile out of liver cells.<\/p>\n\n\n\n